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Neuropathic pain – Factors, Symptoms, Diagnose, Treatment

What is neuropathic pain and how does it develop?

Neuropathic pain is pain due to injury or malfunction of the nervous system. Noxious (pain-inducing) stimuli are not the source of the discomfort. Erroneous nervous system signals are to blame for the pain.

Unlike physiologic pain, which serves to alert and protect people from potential or actual damage, neuropathic pain is useless.

Pain after a stroke; pain after a spinal cord injury is two examples of central neuropathic pain. You can also use nervigesic 150mg to cure neuropathic pain.


  • Chronic pain affects one out of every five Australians. It will be present in many of these individuals, adding to their total pain condition.
  • Over half of all individuals with persistent low back pain, for example, have a strong neuropathic component to their pain.
  • Neuropathy has connected to a number of risk factors.
  • The underlying source of the pain determines the risk factors for the development of neuropathic pain.
  • The development of shingles on the face, for example, is a risk factor for developing post-herpetic neuralgia, while diabetes mellitus is a risk factor for developing diabetic neuropathy.


Patients typically describe neuropathic pain as “searing,” “shooting,” or even “electric.” Strange sensations such as cold, numbness, tingling, pins & needles, or itching may accompany the pain in the afflicted region.

The following are some more frequent pain sensations:

  • Hyperalgesia is a word that refers to an exaggerated sensitivity to painful stimuli (when a stimulus that normally produces moderate discomfort generates significant pain).
  • Hyperalgesia is a medical condition that causes the body’s sensitivity to painful stimuli to decrease.
  • Hypoaesthesia refers to a loss of touch sensitivity.
  • Paraesthesia refers to abnormal but non-painful feelings.
  • Synaesthesia is an unpleasant, unnatural feeling that may occur spontaneously or in reaction to contact.
  • Hyperpathia is a word that refers to a heightened reactivity to painful input, especially a recurring painful stimulus, as well as an increased pain threshold.

Studied in a clinical setting

  • During a clinical examination for neuropathic pain, a complete neurological (nervous system) evaluation is necessary.
  • This is done to determine if any regions of sensory impairment exist.
  • Different sorts of stimuli are given to the skin (such as heat, cold, pinprick, and vibration), and the patient’s reaction is recorded as normal, decreased, or increased.

Clinical examination findings differ depending on the condition. Apart from indications of Allodynia, Hyperalgesia, and hyperpathia, an examination may be totally normal.

How can you know whether you’re experiencing it?

  • Investigations may be useful in discovering the underlying cause of pain, and they should concentrate on suspected causes. Blood tests are usually necessary.
  • In certain circumstances, electromyography and nerve conduction investigations may be beneficial.

Neuropathic pain prognosis

The prognosis varies depending on the kind of discomfort. Overall, though, neuropathic pain is notoriously difficult to manage.

It may be treated in a number of different ways.

  • Neuropathic pain is a tough condition to treat. If it is possible, the source of the pain should be looked at, but this isn’t always the case.
  • Non-pharmacological and pharmacological treatment methods are available.


Many anticonvulsant medications have been tried but unsuccessful in the treatment of neuropathic pain. You can buy nervigesic 150mg from PillsPalace site.

When used to treat post-herpetic neuralgia and diabetic neuropathy, pregabalin (Lyrica), a new medication with a similar mechanism of action to gabapentin, has a number required to treat (NNT) of just 4.3.


  • the first-line treatment for neuropathic pain has traditionally been amitriptyline and other tricyclic antidepressants.
  • Low dosages may generally reduce pain while avoiding unpleasant side effects such as dry mouth, impaired vision, urine retention, and low blood pressure.

Other prescription drugs

  • The evidence for these drugs’ usage isn’t as strong. In situations of refractory pain, a referral to a multidisciplinary pain treatment center may be beneficial.
  • In carefully chosen circumstances, certain centers may be able to provide additional therapy alternatives such as spinal cord stimulation.

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